Why are hormone pellets so popular?

By May 11, 2018 No Comments
Happy Couple Using Hormone Pellets

Have you heard about hormone pellets?  Here is why you may be interested  in learning more.

Hormones change as you age

As we age, things change.  One of those changes is a drop in our hormone levels!  Hormones, like estrogen and testosterone,  affect your energy, mood, memory, sex drive, and metabolism. (Did you know that the average woman gains 20 pounds as she goes through menopause and has three times the risk of depression?) Problems with your hormones affect the health of your skin, hair, and nails, and increase your risk of diseases like osteoporosis, dementia, and heart disease.

Bio-identical hormone therapy can help!

Bio-identical hormone replacement therapy can help you get back to feeling like yourself again!

When I started my practice in 2007, I mostly prescribed topical bio-identical hormone creams. This allowed me to prescribe the right mixture of hormones based on your unique needs (a pinch of estrogen, a dollop of progesterone and just a drop of testosterone, for example!).  It worked well – but not everyone had great results. In 2009, I started offering hormone pellet therapy, and now 70% of my patients prefer pellets to topical cream.

Hormone pellets are smaller than a grain of rice, contain a natural plant source of estrogen and/or testosterone, and are available in a variety of doses. They are inserted under the skin of your buttock in a simple, painless office procedure. The pellets gradually dissolve, and a small, steady stream of hormone is released into the bloodstream.

Pellets can fix hormone symptoms fast – sometimes within 48 hours!  The convenience is very popular – you simply come in every 3-4 months to have the pellet replaced.

Hormone pellets can help resolve your symptoms

Hormone pellets can  help with a wide variety of symptoms including:

– insomnia

– fatigue

– low sex drive

– lack of motivation

– hot flashes and night sweats

– heart palpitations

– headaches (especially premenstrual or hormonal migraines)

– irritability/mood swings

– depression

– anxiety

– memory loss

– leakage of urine

– aches and pains

– vaginal dryness

– lack of muscle tone

– dry skin and hair

– loss of strength

Pellets help with Low T

Bio-identical testosterone pellets are popular with men too.  They help men with the same symptoms! (just swap out vaginal dryness for erectile function!)

Are pellets safe?

This treatment seems “new” but in fact hormone pellets have been used with great success in the United States, Europe and Australia since 1938! Pellets deliver consistent, steady levels of hormones and avoid the fluctuations of hormone levels seen with other kinds of hormone replacement, like topical creams.

Hormones delivered by pellets bypass the liver, and don’t increase the risk of blood clots (which is a problem with estrogen pills).

Medical studies have found that hormone pellets are very effective at preventing and treating bone loss and for relieving menopausal symptoms, with even better success than pills or creams in some cases.  This is why they have become the most popular method of bio-identical hormone replacement in my practice – patients  are getting better results!

Pellets do not have the same risk of breast cancer as synthetic hormone replacement pills.  In fact, some studies show there may be a reduction in the incidence of breast cancer with pellet therapy. In a study on breast cancer survivors, testosterone pellets did not increase the risk of cancer recurrence.

I have listed some medical studies on hormone pellets below.

You have choices!

There are many options for bio-identical hormone replacement therapy including topical or vaginal creams, patches, pills, sublingual lozenges and pellets.  It is nice to have choices, and important to have thorough discussion of all your options, including all the risks, benefits and possible side effects, so you can make the best choice!

Wondering whether your symptoms could be due to hormone deficiency?  Take our hormone quiz! Please don’t suffer with symptoms due to hormone deficiencies.  You deserve to LOVE the way you feel!

Yours in health!

Dr Deb Matthew MD


Beneficial effects of testosterone therapy in women measured by the validated Menopause Rating Scale (MRS)Glaser R, York AE, Dimitrakakis C. Maturitas. 20011;68:355-361

“Testosterone, delivered by subcutaneous pellet implant has been shown to improve hot flashes, heart discomfort, sleep problems, depressive mood, irritability, anxiety, physical fatigue, memory loss, migraine headaches, sexual problems, bladder problems (incontinence), vaginal dryness, joint and muscular discomfort in both pre-menopausal and post-menopausal patients without adverse drug events”

Moderate dosage estrogen–androgen therapy improves continuation rates in postmenopausal women: impact of the WHI reports Gambrell and Natrajan CLIMACTERIC 2006;9:224–233

“Long-term studies with up to 30 years follow up, confirm the safety of testosterone therapy and absence of adverse drug events with the pellet implant.   No increase of breast cancer even after 20 years of hormone pellet therapy”

Skeletal effects of oral oestrogen compared with subcutaneous oestrogen and testosterone in postmenopausal women.  Savvas et al.  British Medical Journal 1988  Jul 30;297(6644): 331-333

“Subcutaneous oestrogen is more effective than oral oestrogen in preventing osteoporosis, probably owing to the more physiological (premenopausal) serum oestradiol concentrations achieved.”

Reduced breast cancer incidence in women treated with subcutaneous testosterone, or testosterone with anastrozole:  a prospective, observational study.  Glaser et al.  Maturitas 2013 Dec;76(4):342-9

“Testosterone and/or testosterone+anastrozole, delivered subcutaneously as a pellet implant, reduced the incidence of breast cancer in pre and postmenopausal women.”